Alkylation of Ethyl 2-Aryl-1-hydroxy-4-methyl-1Н-imidazole-5-carboxylates with Benzyl Halides

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Дәйексөз келтіру

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Аннотация

Alkylation of ethyl 2-aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylates with substituted benzyl halides led to the selective formation of O-alkoxy derivatives. Products of N-alkylation (1-alkylimidazole 3-oxides) could be obtained by condensation reaction from acyclic starting compounds. If a 2-hydroxyphenyl moiety was present in position 2 of imidazole ring, then monoalkylation proceeded selectively at hydroxy group of the nitrogen atom of heterocycle.

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Авторлар туралы

Polina Nikitina

Mendeleev University of Chemical Technology of Russia

Хат алмасуға жауапты Автор.
Email: polinandrevna@yandex.ru
ORCID iD: 0000-0003-1542-5565
Ресей, 9, Miusskaya Sqr., Moscow, 125047

Irina Oskina

Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the RAS

Email: polinandrevna@yandex.ru
ORCID iD: 0000-0001-5788-0182
Ресей, 9, Ac. Lavrentyev Ave., Novosibirsk, 630090

Elena Nikolaenkova

Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the RAS

Email: polinandrevna@yandex.ru
ORCID iD: 0009-0000-5034-8513
Ресей, 9, Ac. Lavrentyev Ave., Novosibirsk, 630090

Ekaterina Kulikova

Mendeleev University of Chemical Technology of Russia

Email: polinandrevna@yandex.ru
ORCID iD: 0009-0009-2311-395X
Ресей, 9, Miusskaya Sqr., Moscow, 125047

Vladimir Miroshnikov

Mendeleev University of Chemical Technology of Russia

Email: polinandrevna@yandex.ru
ORCID iD: 0000-0003-3815-7479
Ресей, 9, Miusskaya Sqr., Moscow, 125047

Valery Perevalov

Mendeleev University of Chemical Technology of Russia

Email: polinandrevna@yandex.ru
ORCID iD: 0000-0002-3980-6496
Ресей, 9, Miusskaya Sqr., Moscow, 125047

Alexey Tikhonov

Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of the RAS

Email: polinandrevna@yandex.ru
ORCID iD: 0000-0002-6391-4366
Ресей, 9, Ac. Lavrentyev Ave., Novosibirsk, 630090

Әдебиет тізімі

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