Reaction of 1-Antipyryl-4-aroyl-5-methoxycarbonyl-1H-pyrrole-2,3-diones with Ethylenediamine

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Abstract

Methyl 3-aroyl-2,4-dihydroxy-1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylates react with ethylenediamine to form methyl 5-aryl-8-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-6,7-dioxo-2,3,4,6,7,8-hexahydropyrrolo[2,3-e] [1,4]diazepine-8a(1H)-carboxylates, the structure of which was confirmed by NMR 1H and IR spectroscopy.

About the authors

V. A Lyadov

Perm National Research Polytechnic University

Email: vadim.lyadov2017@yandex.ru
ORCID iD: 0000-0002-7267-7577
Perm, Russia

N. V Shavrina

Perm National Research Polytechnic University

ORCID iD: 0000-0002-1702-2332
Perm, Russia

E. S Denislamova

Perm National Research Polytechnic University

ORCID iD: 0000-0003-1220-3625
Perm, Russia

A. N Maslivets

Perm State University

ORCID iD: 0000-0001-7148-4450
Perm, Russia

References

  1. Машковский М.Д. Лекарственные средства. М.: Новая волна. 2011, 164–166.
  2. Червяков А.В. Автореф. дис. ... канд. хим. наук. Пермь. 2017.
  3. Денисламова Е.С., Лядов В.А., Макрушин Д.Е., Рабов В.Г., Дмитриев М.В., Масливец А.Н. ЖОрХ. 2023, 59, 535–540. doi: 10.31857/S0514749223040122.

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